INT292659

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Context Info
Confidence 0.47
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.59
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (FOLR1) extracellular region (FOLR1) plasma membrane (FOLR1)
Anatomy Link Frequency
T cells 2
FOLR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 1 95.72 Very High Very High Very High
cytokine 19 84.08 Quite High
Inflammation 12 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometrial Cancer 153 99.84 Very High Very High Very High
Neuritis 1 95.72 Very High Very High Very High
Colitis 1 94.76 High High
Graft Vs Host Disease 2 89.40 High High
Apoptosis 16 72.44 Quite High
Aneuploidy 3 70.00 Quite High
Malignant Neoplastic Disease 18 68.72 Quite High
Congenital Anomalies 2 65.48 Quite High
Microsatellite Instability 47 46.32 Quite Low
Adenocarcinoma 6 39.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intestinal trefoil protein, TFF3, AGR2 developmental gene, estrogen-regulated genes (MGB2, LTF, END1, MMP11), FOXA2, and MSX2 were significantly up-regulated in endometrioid endometrial carcinomas, while increased expression of FOLR, genes involved in the regulation of mitotic spindle checkpoint (STK15, BUB1, CCNB2), IGF2, PTGS1 and p16 were seen in non-endometrioid endometrial carcinomas.
Positive_regulation (increased) of Gene_expression (expression) of FOLR associated with endometrial cancer
1) Confidence 0.47 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 1.22 Pain Relevance 0
RII-transfected fibroblasts, induces naïve or memory CD4+ T cells to produce IL-9 [14].
Positive_regulation (induces) of Gene_expression (produce) of cells in T cells
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806834 Disease Relevance 0.36 Pain Relevance 0.14

General Comments

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