INT292705

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hsf1) DNA binding (Hsf1) protein complex (Hsf1)
response to stress (Hsf1) cytoplasm (Hsf1)
Hsf1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 1 5.88 Low Low
Disease Link Frequency Relevance Heat
Chronic Myeloid Leukemia 8 98.98 Very High Very High Very High
Shock 7 97.42 Very High Very High Very High
Myeloid Leukemia 12 82.40 Quite High
Congenital Anomalies 1 80.52 Quite High
Philadelphia Chromosome 2 69.12 Quite High
Genetic Translocation 1 66.52 Quite High
Apoptosis 8 53.28 Quite High
Blast Crisis 1 40.64 Quite Low
Disease 1 36.64 Quite Low
Cancer 5 21.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of the heat-shock protein 70 is associated with Imatinib resistance in chronic myeloid leukemia [15].We have previously reported that Resveratrol alters sub cellular localization, transcriptional activity, and promoter binding of the HSF1 that in turn downregulates gene expression of hsp70 [11].
Regulation (alters) of HSF1 Binding (binding) of associated with shock and chronic myeloid leukemia
1) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806839 Disease Relevance 0.89 Pain Relevance 0

General Comments

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