INT292750

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.67
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Akt1, Bcl2) nucleus (Akt1, Bcl2) cytoplasm (Akt1, Bcl2)
cytosol (Akt1, Bcl2) nucleoplasm (Akt1) mitochondrion (Bcl2)
Anatomy Link Frequency
cardiac myocytes 1
Akt1 (Rattus norvegicus)
Bcl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 18 88.72 High High
Inflammation 18 43.60 Quite Low
depression 2 25.84 Quite Low
cytokine 6 9.76 Low Low
cva 24 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Thoracotomy 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypothermia 138 99.78 Very High Very High Very High
Hemorrhagic Shock 18 99.34 Very High Very High Very High
Apoptosis 9 96.04 Very High Very High Very High
Cv Unclassified Under Development 16 88.72 High High
Stress 3 85.88 High High
Death 9 84.80 Quite High
Cv General 4 Under Development 1 57.04 Quite High
Injury 61 50.00 Quite Low
Hemorrhage 46 50.00 Quite Low
Brain Injury 4 47.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In rodent model of hemorrhagic shock, profound hypothermia preserved Akt in cardiac myocytes, activated pro-survival proteins including Bcl-2 and beta catenin and suppressed Bad and caspase-3 activation [101].
Akt Positive_regulation (activated) of Bcl-2 in cardiac myocytes associated with hypothermia and hemorrhagic shock
1) Confidence 0.01 Published 2009 Journal Scand J Trauma Resusc Emerg Med Section Body Doc Link PMC2806855 Disease Relevance 1.67 Pain Relevance 0.15

General Comments

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