INT292781

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Kcnn3) cytoplasm (Kcnn3)
Kcnn3 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sickle Cell Anemia 4 97.36 Very High Very High Very High
Volume Depletion And Dehydration 11 96.88 Very High Very High Very High
Hypoxia 10 92.76 High High
Death 1 37.48 Quite Low
Disease 10 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Hemolytic Anemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The deoxygenation-activated conductance is likely responsible for [Ca2+]i elevation in human and mouse sickle cells, leading to activation of KCa3.1 (Gardos channel), with consequent acceleration of pathological sickle cell dehydration.
Positive_regulation (leading) of Positive_regulation (activation) of KCa3 associated with sickle cell anemia and volume depletion and dehydration
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806905 Disease Relevance 0.49 Pain Relevance 0

General Comments

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