INT292816

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (KCNJ11) small molecule metabolic process (KCNJ11) endoplasmic reticulum (KCNJ11)
nucleus (FTO) plasma membrane (KCNJ11) neurological system process (KCNJ11)
Anatomy Link Frequency
body 1
KCNJ11 (Homo sapiens)
FTO (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 9 95.64 Very High Very High Very High
corticosteroid 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 9 100.00 Very High Very High Very High
Impaired Glucose Tolerance 9 95.96 Very High Very High Very High
Diabetes Mellitus 103 94.96 High High
Disorder Of Lipid Metabolism 1 83.36 Quite High
Disease 14 5.00 Very Low Very Low Very Low
Coronary Artery Disease 7 5.00 Very Low Very Low Very Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
Cardiovascular Disease 3 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In line with previous reports, FTO rs1421085 was associated with body mass index (P<0.001).30 CDC123/CAMK10 rs10811661 (P=0.001), KCNJ11 rs5219 (P<0.01), and TCF7L2 rs7901695 (P<0.002) were associated with two hour glucose after an oral glucose tolerance test.
KCNJ11 Binding (associated) of FTO in body associated with obesity, tolerance and impaired glucose tolerance
1) Confidence 0.46 Published 2010 Journal BMJ : British Medical Journal Section Body Doc Link PMC2806945 Disease Relevance 0.49 Pain Relevance 0.05

General Comments

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