INT292827

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.21
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Pcyt1a) biosynthetic process (Pcyt1a) nucleotidyltransferase activity (Pcyt1a)
cytoplasm (Pcyt1a)
Anatomy Link Frequency
T cells 1
Pcyt1a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 24 97.36 Very High Very High Very High
Inflammation 9 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 434 100.00 Very High Very High Very High
Necrosis 2 97.52 Very High Very High Very High
Atherosclerosis 22 50.00 Quite Low
Disorder Of Lipid Metabolism 15 50.00 Quite Low
Hyperlipidemia 13 50.00 Quite Low
Targeted Disruption 4 50.00 Quite Low
Atherosclerotic Plaque 4 30.08 Quite Low
INFLAMMATION 17 5.00 Very Low Very Low Very Low
Metastasis 10 5.00 Very Low Very Low Very Low
Bronchopulmonary Dysplasia 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We observed that PDT treatment of antigen positive CT26.CL25 (but not antigen-negative CT26WT) tumors led to striking and significant (p<0.001) increases in tumor necrosis factor alpha (TNF?)
Neg (not) Positive_regulation (tumors) of CT26 associated with necrosis and cancer
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001867 Disease Relevance 1.19 Pain Relevance 0.09
In addition, the LAPM-1 staining demonstrated that contralateral (Figure 5D&F) antigen positive CT26.CL25 tumors are also heavily infiltrated by LAMP-1 positive T cells.
Positive_regulation (infiltrated) of CT26 in T cells associated with cancer
2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001867 Disease Relevance 1.02 Pain Relevance 0
Per2 mRNA level was decreased at CT0 and CT4 in apoE-/-mice, in contrast, which was increased at CT12 and CT16, compared to C57BL/6J mice (Fig. 4).
Positive_regulation (increased) of CT16
3) Confidence 0.03 Published 2009 Journal Lipids Health Dis Section Body Doc Link PMC2807425 Disease Relevance 0 Pain Relevance 0

General Comments

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