INT292852

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.56
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gfm1) intracellular (Gfm1) translation (Gfm1)
GTPase activity (Gfm1)
Gfm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 33 84.44 Quite High
Inflammatory response 13 65.80 Quite High
ischemia 3 63.04 Quite High
alcohol 14 50.00 Quite Low
anesthesia 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 59 100.00 Very High Very High Very High
Apoptosis 59 99.56 Very High Very High Very High
Sprains And Strains 74 97.64 Very High Very High Very High
Influenza Virus Infection 26 88.16 High High
INFLAMMATION 42 84.44 Quite High
Stress 8 68.64 Quite High
Reperfusion Injury 2 63.80 Quite High
Hypertrophic Cardiomyopathy 1 62.52 Quite High
Cleidocranial Dysplasia 1 61.36 Quite High
Myocardial Infarction 3 60.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The fact that the ADH transgene augmented the ethanol-induced cytosolic accumulation of pro-caspase-9 and cytochrome C further substantiated the critical role of acetaldehyde in ethanol-induced mitochondrial damage, which is consistent with the ADH-accentuated mitochondrial O2•?
Positive_regulation (induced) of mitochondrial Binding (damage) of
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2807457 Disease Relevance 1.23 Pain Relevance 0.06
However, induction of cell death via mitochondrial association was specific only to the PB1-F2 protein of the laboratory strain of PR8 in these studies and is not a general property of all PB1-F2 proteins.
Positive_regulation (induction) of mitochondrial Binding (association) of associated with sprains and strains and death
2) Confidence 0.00 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2908617 Disease Relevance 1.32 Pain Relevance 0.11

General Comments

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