INT292920

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.49
Pain Relevance 1.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
motoneuron 2
Syt12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 52 100.00 Very High Very High Very High
opiate 32 99.82 Very High Very High Very High
opioid receptor 30 99.80 Very High Very High Very High
Analgesic 6 95.76 Very High Very High Very High
Opioid 30 95.32 Very High Very High Very High
agonist 8 81.28 Quite High
Glutamate receptor 4 49.16 Quite Low
analgesia 8 43.60 Quite Low
tetrodotoxin 18 5.00 Very Low Very Low Very Low
Glutamate 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 46 100.00 Very High Very High Very High
Respiratory Failure 6 5.00 Very Low Very Low Very Low
Sleep Disorders 4 5.00 Very Low Very Low Very Low
Apnoea 4 5.00 Very Low Very Low Very Low
Central Sleep Apnea 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that ampakines may be beneficial in countering opiate-induced suppression of XII motoneuron activity and resultant impairment of airway patency.



Negative_regulation (suppression) of XII motoneuron in motoneuron associated with opiate
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2808240 Disease Relevance 0.24 Pain Relevance 0.66
-opioid receptor-mediated depression of XII motoneuron inspiratory activity.
Negative_regulation (depression) of XII motoneuron in motoneuron associated with depression and opioid receptor
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2808240 Disease Relevance 0.25 Pain Relevance 0.62

General Comments

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