INT292922

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.12 Pain Relevance 0.19

signal transducer activity (Olr717)

Olr717 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Glutamate 8 98.96 depression 26 65.36 opiate 16 50.00 repetitive firing 1 32.40 opioid receptor 15 5.00 Opioid 15 5.00 tetrodotoxin 9 5.00 analgesia 4 5.00 agonist 4 5.00 Analgesic 3 5.00

Disease Link Frequency Relevance Heat Depression 23 65.36 Respiratory Failure 3 5.00 Sleep Disorders 2 5.00 Apnoea 2 5.00 Central Sleep Apnea 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The mechanisms by which CX717 and other low-impact AMPAKINES produce their actions are less well understood than for high impact AMPAKINES.

Gene_expression (produce) of CX717

1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2808240 Disease Relevance 0.12 Pain Relevance 0.19

General Comments

This test has worked.