INT292988

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SGCG, GABRB3) signal transduction (GABRB3) transport (GABRB3)
cytoskeleton (SGCG) cytoskeleton organization (SGCG) transmembrane transport (GABRB3)
Anatomy Link Frequency
spinal 2
SGCG (Homo sapiens)
GABRB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
GABAergic 4 100.00 Very High Very High Very High
spinal dorsal horn 2 98.88 Very High Very High Very High
Neuropathic pain 3 95.56 Very High Very High Very High
unmyelinated 38 90.64 High High
interneuron 1 90.08 High High
nociceptor 2 88.04 High High
Action potential 6 76.80 Quite High
Peripheral nerve injury 2 69.68 Quite High
Inflammatory mediators 1 67.96 Quite High
dorsal root ganglion 13 65.52 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 4 95.56 Very High Very High Very High
Nervous System Injury 2 69.68 Quite High
INFLAMMATION 2 67.56 Quite High
Ganglion Cysts 13 65.52 Quite High
Amputation 1 25.36 Quite Low
Nociception 8 19.44 Low Low
Neuropathy 1 10.40 Low Low
Disease 1 5.04 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed current therapeutic strategies currently being developed in mice are aimed at reversing this GABAergic disinhibition through sub-type selective activation of GABAA receptors expressed in the spinal dorsal horn [50].
Negative_regulation (reversing) of type Positive_regulation (activation) of GABAA in spinal associated with spinal dorsal horn and gabaergic
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2808338 Disease Relevance 0.30 Pain Relevance 0.89

General Comments

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