INT293048

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (PRNP) endoplasmic reticulum (PRNP) nucleolus (PRNP)
plasma membrane (PRNP) nucleus (PRNP) cell cycle (PRNP)
PRNP (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 7 5.00 Very Low Very Low Very Low
Hippocampus 7 5.00 Very Low Very Low Very Low
Thalamus 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Sciatic nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 31 99.76 Very High Very High Very High
Disease 34 96.36 Very High Very High Very High
Prion Diseases 27 89.24 High High
Creutzfeldt Jakob Disease 4 72.00 Quite High
Proteostasis Deficiencies 1 35.84 Quite Low
Neurodegenerative Disease 2 33.60 Quite Low
Infection 8 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 6 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 4 5.00 Very Low Very Low Very Low
Scrapie 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because of its unique features, the SSLOW strain may prove to be a valuable model for addressing a number of puzzling questions of prion biology: what factors determine prion neurotropism; how strain-specific PrPSc structures control the rate of prion replication; why clinical disease could progresses so slowly despite large amounts of PrPSc deposition; and the physical nature of toxic versus infectious PrP isoforms.
Spec (determine) Regulation (determine) of Spec (determine) Protein_catabolism (neurotropism) of prion associated with disease and sprains and strains
1) Confidence 0.06 Published 2010 Journal Acta Neuropathol Section Body Doc Link PMC2808531 Disease Relevance 1.01 Pain Relevance 0

General Comments

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