INT29305

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 1986
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 0.73
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
monocyte 2
CPA 1
lymphocyte 1
Pt (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 3 99.90 Very High Very High Very High
Opioid 1 83.36 Quite High
interneuron 10 61.96 Quite High
withdrawal 4 50.96 Quite High
Inflammation 34 48.40 Quite Low
addiction 4 8.84 Low Low
Spinal cord 12 5.00 Very Low Very Low Very Low
cva 12 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 2 82.00 Quite High
Necrosis 14 73.64 Quite High
Cancer 2 73.28 Quite High
Targeted Disruption 4 65.04 Quite High
Stress 10 62.88 Quite High
Toxicity 16 56.28 Quite High
Sprains And Strains 32 54.72 Quite High
INFLAMMATION 38 48.40 Quite Low
Hepatotoxicity 8 46.68 Quite Low
Adhesions 8 17.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mice, with more pronounced induction of PH and PT mRNA in mPPAR?
Positive_regulation (induction) of PT
1) Confidence 0.37 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.19 Pain Relevance 0
target genes VLCAD, MCAD, PH, and PT were increased with TRI exposure relative to controls in mPPAR?
Positive_regulation (increased) of PT
2) Confidence 0.32 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.20 Pain Relevance 0
Cellular L-arginine, RNS and L-citrulline contents of platelet, neutrophil and monocyte were gradually increased in 18 days pt (with exception for monocyte, in which arginine content was slightly decreased 9 day pt), while those of lymphocyte and marrow reduced 9 day pt and elevated 18 day pt (Figs. 3-5).
Positive_regulation (elevated) of pt in monocyte
3) Confidence 0.10 Published 2008 Journal The Open Biochemistry Journal Section Body Doc Link PMC2570548 Disease Relevance 0 Pain Relevance 0
Cellular L-arginine, RNS and L-citrulline contents of platelet, neutrophil and monocyte were gradually increased in 18 days pt (with exception for monocyte, in which arginine content was slightly decreased 9 day pt), while those of lymphocyte and marrow reduced 9 day pt and elevated 18 day pt (Figs. 3-5).
Positive_regulation (increased) of pt in monocyte
4) Confidence 0.10 Published 2008 Journal The Open Biochemistry Journal Section Body Doc Link PMC2570548 Disease Relevance 0 Pain Relevance 0
Though, L-arginine and NOS cofactors increase the iNOS activity of lymphocyte, as well as that of neutrophil 9 day pt, suggesting the negative effects of bivalent cations on the NOSs with possible involvement of NADPH oxidase activated by calcium.
Positive_regulation (increase) of pt in lymphocyte
5) Confidence 0.07 Published 2008 Journal The Open Biochemistry Journal Section Body Doc Link PMC2570548 Disease Relevance 0.07 Pain Relevance 0.03
Thus, PN formation by blood cells could be occurred due to activation of cellular NADPHoxidase in CPA-treated rats 9 day pt.
Positive_regulation (activation) of pt in CPA
6) Confidence 0.07 Published 2008 Journal The Open Biochemistry Journal Section Body Doc Link PMC2570548 Disease Relevance 0.12 Pain Relevance 0
Accordingly, in Fig. 5A, the color of the symbols indicates whether cells received excitatory input following PT or MLF stimulation alone or to both types of stimuli, according to the key at the bottom right of the plot.
Spec (whether) Positive_regulation (stimulation) of PT
7) Confidence 0.06 Published 2010 Journal Journal of Neurophysiology Section Body Doc Link PMC2867561 Disease Relevance 0 Pain Relevance 0.03
These results suggest that bovine adrenal medullary opioid receptors are linked to PT-sensitive GTP-binding proteins which are not directly coupled to adenylate cyclase.
Positive_regulation (linked) of PT associated with opioid receptor
8) Confidence 0.05 Published 1986 Journal NIDA Res. Monogr. Section Abstract Doc Link 2828956 Disease Relevance 0.16 Pain Relevance 0.21

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox