INT293345

Context Info Confidence 0.02 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.19 Pain Relevance 0.13

isomerase activity (FKBP1A) protein folding (FKBP1A) cytosol (FKBP1A) signal transduction (FKBP1A) cytoplasm (FKBP1A) signal transducer activity (FKBP1A)

FKBP1A (Homo sapiens)

Pain Link Frequency Relevance Heat Bile 1 79.52 alcohol 1 69.12 Bioavailability 6 58.12 fibrosis 10 33.80 corticosteroid 37 5.00 cytokine 19 5.00 Inflammation 10 5.00 Paracetamol 3 5.00 Antihistamine 2 5.00 agonist 2 5.00

Disease Link Frequency Relevance Heat Organ Transplantation 5 97.56 Body Weight 1 89.12 Cirrhosis 8 36.00 Fibrosis 8 20.16 Renal Failure 11 10.24 Fungal Infection 2 6.12 Hepatitis C Virus Infection 52 5.00 Recurrence 23 5.00 Nephrotoxicity 13 5.00 INFLAMMATION 10 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The 50% inhibitory concentration for sirolimus inhibition of FK506 binding to FK506 binding protein 12 is approximately 0.4–0.9 nano moles per liter (nmol/L).

Negative_regulation (inhibition) of FK506 binding protein Binding (binding) of

1) Confidence 0.02 Published 2009 Journal Journal of Transplantation Section Body Doc Link PMC2809333 Disease Relevance 0.19 Pain Relevance 0.13

General Comments

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