INT293355

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Fkbp1a, CABIN1) isomerase activity (Fkbp1a) protein folding (Fkbp1a)
cytosol (Fkbp1a) signal transduction (Fkbp1a) nucleolus (CABIN1)
Anatomy Link Frequency
T cell 1
Fkbp1a (Mus musculus)
CABIN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 37 19.88 Low Low
cytokine 19 5.00 Very Low Very Low Very Low
fibrosis 10 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Organ Transplantation 5 63.88 Quite High
Autoimmune Disease 1 53.48 Quite High
Fungal Infection 2 46.00 Quite Low
Disease 8 18.64 Low Low
Hepatitis C Virus Infection 52 15.28 Low Low
Recurrence 23 5.00 Very Low Very Low Very Low
Nephrotoxicity 13 5.00 Very Low Very Low Very Low
Renal Failure 11 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Fibrosis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Csa and tacrolimus (which inhibit the phosphatase calcineurin after binding to heir respective immunophilins FKBP and cyclophilin, respectively) inhibit early events in T cell activation particularly the expression of IL-2 in the G0-G1 stage of the cell cycle.
FKBP Binding (binding) of calcineurin in T cell
1) Confidence 0.00 Published 2009 Journal Journal of Transplantation Section Body Doc Link PMC2809333 Disease Relevance 0.12 Pain Relevance 0

General Comments

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