INT293358

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (FKBP1A, CABIN1) isomerase activity (FKBP1A) protein folding (FKBP1A)
cytosol (FKBP1A) signal transduction (FKBP1A) nucleolus (CABIN1)
FKBP1A (Homo sapiens)
CABIN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 19 52.32 Quite High
corticosteroid 37 24.12 Low Low
fibrosis 10 21.92 Low Low
Inflammation 10 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Organ Transplantation 5 71.12 Quite High
Toxicity 1 41.56 Quite Low
Fibrosis 8 21.92 Low Low
Hepatitis C Virus Infection 52 5.00 Very Low Very Low Very Low
Recurrence 23 5.00 Very Low Very Low Very Low
Nephrotoxicity 13 5.00 Very Low Very Low Very Low
Renal Failure 11 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 8 5.00 Very Low Very Low Very Low
Cirrhosis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Csa and tacrolimus are calcineurin inhibitors that bind to their specific immunophilins, cyclophilin and FK binding protein, respectively, before the drug-receptor complex binds to and inhibits calcineurin, a calcium-dependent phosphatase.
FK binding protein Binding (bind) of calcineurin
1) Confidence 0.00 Published 2009 Journal Journal of Transplantation Section Body Doc Link PMC2809333 Disease Relevance 0.07 Pain Relevance 0.03

General Comments

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