INT293360

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.14
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CSH1, FKBP1A) isomerase activity (FKBP1A) protein folding (FKBP1A)
cytosol (FKBP1A) extracellular region (CSH1) cytoplasm (FKBP1A)
CSH1 (Homo sapiens)
FKBP1A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 38 56.64 Quite High
fibrosis 20 26.24 Quite Low
corticosteroid 74 25.04 Quite Low
Inflammation 20 5.00 Very Low Very Low Very Low
Bioavailability 12 5.00 Very Low Very Low Very Low
Paracetamol 6 5.00 Very Low Very Low Very Low
Antihistamine 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Organ Transplantation 10 72.04 Quite High
Toxicity 2 42.48 Quite Low
Fibrosis 16 26.24 Quite Low
Hepatitis C Virus Infection 104 5.00 Very Low Very Low Very Low
Recurrence 46 5.00 Very Low Very Low Very Low
Nephrotoxicity 26 5.00 Very Low Very Low Very Low
Renal Failure 22 5.00 Very Low Very Low Very Low
INFLAMMATION 20 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 16 5.00 Very Low Very Low Very Low
Cirrhosis 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Csa and tacrolimus are calcineurin inhibitors that bind to their specific immunophilins, cyclophilin and FK binding protein, respectively, before the drug-receptor complex binds to and inhibits calcineurin, a calcium-dependent phosphatase.
Csa Binding (bind) of FK binding protein
1) Confidence 0.00 Published 2009 Journal Journal of Transplantation Section Body Doc Link PMC2809333 Disease Relevance 0.07 Pain Relevance 0.03
Csa and tacrolimus are calcineurin inhibitors that bind to their specific immunophilins, cyclophilin and FK binding protein, respectively, before the drug-receptor complex binds to and inhibits calcineurin, a calcium-dependent phosphatase.
Csa Binding (binds) of FK binding protein
2) Confidence 0.00 Published 2009 Journal Journal of Transplantation Section Body Doc Link PMC2809333 Disease Relevance 0.07 Pain Relevance 0.03

General Comments

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