INT293366

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CABIN1, Fkbp1a) isomerase activity (Fkbp1a) enzyme binding (Fkbp1a)
signal transducer activity (Fkbp1a) cytosol (Fkbp1a) protein folding (Fkbp1a)
CABIN1 (Homo sapiens)
Fkbp1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 37 9.04 Low Low
cytokine 19 5.00 Very Low Very Low Very Low
fibrosis 10 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Organ Transplantation 5 53.04 Quite High
Autoimmune Disease 1 42.64 Quite Low
Fungal Infection 2 35.16 Quite Low
Disease 8 7.80 Low Low
Hepatitis C Virus Infection 52 5.00 Very Low Very Low Very Low
Recurrence 23 5.00 Very Low Very Low Very Low
Nephrotoxicity 13 5.00 Very Low Very Low Very Low
Renal Failure 11 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Fibrosis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sirolimus which also binds to the FKBP family, particularly FKBP-12, does not bind to calcineurin but instead binds to target molecules with kinase activity called MTOR (mammalian targets of rapamycin), also known as FRAP and RAFT.
calcineurin Neg (not) Binding (bind) of FKBP-12
1) Confidence 0.00 Published 2009 Journal Journal of Transplantation Section Body Doc Link PMC2809333 Disease Relevance 0.05 Pain Relevance 0

General Comments

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