INT293413

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GOPC, IL11) extracellular space (IL11) extracellular region (IL11)
Golgi apparatus (GOPC) plasma membrane (GOPC) cell-cell signaling (IL11)
GOPC (Homo sapiens)
IL11 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 6 99.00 Very High Very High Very High
Cancer 66 95.80 Very High Very High Very High
Osteolysis 2 94.40 High High
Breast Cancer 24 50.00 Quite Low
Metastasis 26 22.48 Low Low
Adhesions 9 5.00 Very Low Very Low Very Low
Advanced Or Metastatic Breast Cancer 5 5.00 Very Low Very Low Very Low
Hypercalcemia 4 5.00 Very Low Very Low Very Low
Ehlers-danlos Syndrome 3 5.00 Very Low Very Low Very Low
Bone Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While VEGF and IL-11 secretion by MDA-MB231 cells were not affected by the scaffold type (Fig. 5A) and PTHrP was secreted at undetectable levels (<0.3 pM) from either mineralized or non-mineralized tumor models (data not shown), IL-8 secretion was increased by 38% in mineralized scaffolds HA (Fig 5A).
Fig Neg (not) Regulation (affected) of Localization (secretion) of IL-11 associated with cancer
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2809751 Disease Relevance 0.60 Pain Relevance 0

General Comments

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