INT293582

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Nmnat2) biosynthetic process (Nmnat2) nucleus (Nmnat2)
nucleotidyltransferase activity (Nmnat2) cytoplasm (Nmnat2)
Anatomy Link Frequency
neurite 2
Nmnat2 (Mus musculus)
Pain Link Frequency Relevance Heat
induced neuropathy 2 80.76 Quite High
Taxol 2 80.00 Quite High
Multiple sclerosis 1 69.68 Quite High
imagery 5 5.00 Very Low Very Low Very Low
dorsal root ganglion 3 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Sciatic nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 17 96.44 Very High Very High Very High
Stress 3 87.44 High High
Wallerian Degeneration 87 86.56 High High
Neuropathic Pain 2 80.76 Quite High
Stroke 1 71.04 Quite High
Demyelinating Disease 1 69.68 Quite High
Disease 2 36.68 Quite Low
Chronic Disease 1 30.48 Quite Low
Viral Infection 1 18.56 Low Low
Aging 1 12.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The simplest explanation is that this represents accumulation of Nmnat2 in a reduced cellular volume following neurite removal while synthesis continues at pre-injury levels.
Negative_regulation (represents) of Positive_regulation (accumulation) of Nmnat2 in neurite associated with injury
1) Confidence 0.36 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2811159 Disease Relevance 0.78 Pain Relevance 0.26

General Comments

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