INT293615

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (Nmnat2, Nmnat1) nucleus (Nmnat2, Nmnat1) nucleotidyltransferase activity (Nmnat2, Nmnat1)
Golgi apparatus (Nmnat2) cytoplasm (Nmnat2)
Nmnat2 (Mus musculus)
Nmnat1 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 3 24.16 Low Low
imagery 5 5.00 Very Low Very Low Very Low
induced neuropathy 2 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Sciatic nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wallerian Degeneration 87 100.00 Very High Very High Very High
Targeted Disruption 15 82.48 Quite High
Ganglion Cysts 3 24.16 Low Low
Injury 17 5.00 Very Low Very Low Very Low
Death 9 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Blister 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The main known function of the mammalian Nmnat isoforms is NAD+ biosynthesis, and the ability of Nmnat1, Nmnat2, and WldS to delay Wallerian degeneration requires Nmnat enzyme activity [1],[5],[26],[43].
Nmnat2 Positive_regulation (requires) of Nmnat associated with wallerian degeneration
1) Confidence 0.19 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2811159 Disease Relevance 0.79 Pain Relevance 0

General Comments

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