INT293672

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RB1) DNA binding (RB1) nucleus (RB1)
molecular_function (RB1) cell division (RB1) cellular_component (RB1)
RB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 14 40.24 Quite Low
Inflammatory stimuli 2 29.64 Quite Low
Kinase C 14 5.00 Very Low Very Low Very Low
withdrawal 8 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 26 81.00 Quite High
Premature Birth 22 56.96 Quite High
Asymptomatic Infections 18 48.44 Quite Low
INFLAMMATION 20 40.24 Quite Low
Pre-term Labor 4 5.00 Very Low Very Low Very Low
Dysmenorrhea 2 5.00 Very Low Very Low Very Low
Cerebral Palsy 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B activation PRA protein increased 14 fold above baseline (Figure 1A and 1B); PRB mRNA and protein expression increased 4.2 fold (Figure 2A and 2B respectively).
Positive_regulation (increased) of Transcription (expression) of PRB
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2811723 Disease Relevance 0.25 Pain Relevance 0
B activation led to an increase in PRA and PRB mRNA and protein expression.
Positive_regulation (increase) of Transcription (expression) of PRB
2) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2811723 Disease Relevance 0.15 Pain Relevance 0

General Comments

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