INT293780

Context Info Confidence 0.20 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.13 Pain Relevance 0

cytosol (EIF4E) translation (EIF4E) cytoplasm (EIF4E)

EIF4E (Homo sapiens)

Pain Link Frequency Relevance Heat addiction 5 5.00 Pain 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Lung Cancer 1 67.28 Prostate Cancer 27 65.28 Breast Cancer 1 26.56 Targeted Disruption 12 5.00 Cancer 12 5.00 Death 2 5.00 Pain 1 5.00 Metastasis 1 5.00 Hypersensitivity 1 5.00 Shock 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This interaction, which was not included in the model, was at least partially responsible for TOR activation and the eventual liberation of eIF4E.

Positive_regulation (activation) of eIF4E Binding (liberation) of

1) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0.13 Pain Relevance 0

General Comments

This test has worked.