INT293804

Context Info Confidence 0.04 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0

enzyme binding (PTEN, AKT1) cytoplasm (PTEN, AKT1) cytosol (PTEN, AKT1) cell proliferation (PTEN, AKT1) nucleus (PTEN, AKT1) plasma membrane (PTEN, AKT1)

PTEN (Homo sapiens) AKT1 (Homo sapiens)

Pain Link Frequency Relevance Heat addiction 5 5.00 Pain 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Shock 1 68.12 Prostate Cancer 27 50.00 Targeted Disruption 12 33.68 Cancer 12 5.00 Death 2 5.00 Pain 1 5.00 Metastasis 1 5.00 Breast Cancer 1 5.00 Lung Cancer 1 5.00 Hypersensitivity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For example, the formation of PIP3, an early step in the PI3K/Akt signaling axis regulated by PTEN, was found to be highly sensitive in all clones.

PTEN Regulation (regulated) of Akt

1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.