INT293815

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

cytoplasm (MAPK1, CCND3) signal transduction (MAPK1, CCND3) nucleus (MAPK1, CCND3) nucleoplasm (MAPK1) mitochondrion (MAPK1) Golgi apparatus (MAPK1)

MAPK1 (Homo sapiens) CCND3 (Homo sapiens)

Pain Link Frequency Relevance Heat addiction 5 5.00 Pain 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Prostate Cancer 27 50.00 Targeted Disruption 12 5.00 Cancer 12 5.00 Death 2 5.00 Pain 1 5.00 Metastasis 1 5.00 Breast Cancer 1 5.00 Lung Cancer 1 5.00 Hypersensitivity 1 5.00 Shock 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Cyclin D expression was coupled to ERK through the ETS and AP1 transcription factors, both of which activate cyclin D expression [59].

ERK Positive_regulation (coupled) of Gene_expression (expression) of Cyclin D

1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0 Pain Relevance 0

General Comments

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