INT293900

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (TYRP1) extracellular region (IGKC)
TYRP1 (Homo sapiens)
IGKC (Homo sapiens)
Pain Link Frequency Relevance Heat
Tetrahydrobiopterin 16 84.24 Quite High
Neurotransmitter 4 60.48 Quite High
amygdala 18 5.00 Very Low Very Low Very Low
drug abuse 16 5.00 Very Low Very Low Very Low
depression 14 5.00 Very Low Very Low Very Low
Central nervous system 10 5.00 Very Low Very Low Very Low
addiction 8 5.00 Very Low Very Low Very Low
Serotonin 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
monoamine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pheochromocytoma 2 58.76 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 31.28 Quite Low
Suicidal Behaviour 30 5.00 Very Low Very Low Very Low
Drug Dependence 16 5.00 Very Low Very Low Very Low
Depression 14 5.00 Very Low Very Low Very Low
Schizophrenia 12 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 6 5.00 Very Low Very Low Very Low
Contagious Ecthyma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Km(Trp) values for TPH2A and TPH2B were nearly similar (Table 2), but significantly higher for the edited variants, indicating a reduced affinity for the substrate Trp (Table 2).
Trp Regulation (values) of Km
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813293 Disease Relevance 0.06 Pain Relevance 0.12
However, Km(Trp) values for TPH2A and TPH2B were close to the previously reported constants and consistently higher than for TPH1 (Table S3) [20], [39].
Trp Regulation (values) of Km
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813293 Disease Relevance 0.05 Pain Relevance 0.14

General Comments

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