INT293975

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Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (POMC, Mc1r) small molecule metabolic process (POMC) signal transducer activity (Mc1r)
cell-cell signaling (POMC) cytoplasm (POMC) pigmentation (Mc1r)
Anatomy Link Frequency
T cells 1
POMC (Homo sapiens)
Mc1r (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 4 50.00 Quite Low
Inflammation 11 49.92 Quite Low
Arthritis 1 36.04 Quite Low
tolerance 1 25.88 Quite Low
cytokine 1 8.00 Low Low
melanocortin 1 receptor 5 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 16 80.80 Quite High
Cancer 46 76.40 Quite High
INFLAMMATION 12 49.92 Quite Low
Uveitis 1 37.00 Quite Low
Arthritis 1 36.04 Quite Low
Multiple Sclerosis 1 32.92 Quite Low
Colitis 2 31.20 Quite Low
Pressure And Volume Under Development 3 28.56 Quite Low
Skin Cancer 52 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-MSH significantly increased the number of MC-1R expressing CD8+ T cells.
MSH Positive_regulation (increased) of MC-1R in T cells
1) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813861 Disease Relevance 0.34 Pain Relevance 0

General Comments

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