INT293982

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MYC) intracellular (SFRP1) embryo development (SFRP1)
DNA binding (MYC) protein complex (MYC) cytosol (SFRP1)
MYC (Homo sapiens)
SFRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 28 88.28 High High
Adenocarcinoma 1 79.24 Quite High
Hyperplasia 1 78.48 Quite High
Cancer 21 72.84 Quite High
Infection 6 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the case of the SFRP genes and WIF1, this downregulation often occurs through methylation-induced epigenetic silencing [9], [10], and both SFRP1 and DKK have been shown to be transcriptionally repressed by MYC, a well-established breast oncogene [11].
MYC Negative_regulation (repressed) of SFRP1
1) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813871 Disease Relevance 0.62 Pain Relevance 0

General Comments

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