INT294019

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PER1) protein binding transcription factor activity (PER1) cytoplasm (PER1)
signal transducer activity (PER1)
PER1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 10.24 Low Low
cINOD 2 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 21 98.34 Very High Very High Very High
Breast Cancer 28 92.88 High High
Apoptosis 3 82.00 Quite High
Infection 6 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of particular interest, Yang et al provide evidence to suggest that CSNK1E is a cancer-specific essential gene and further postulate that this may be due to its role in regulation of Per1/2 degradation and circadian cycling [35].
Regulation (regulation) of Protein_catabolism (degradation) of Per1 associated with cancer
1) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813871 Disease Relevance 0.86 Pain Relevance 0

General Comments

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