INT294082

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 3.14
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CORO7) Golgi apparatus (CORO7) cytoplasmic membrane-bounded vesicle (CORO7)
cytoplasm (CORO7)
Anatomy Link Frequency
T cells 1
CORO7 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 2 98.60 Very High Very High Very High
iatrogenic 3 76.44 Quite High
Inflammation 39 70.08 Quite High
addiction 36 67.24 Quite High
anesthesia 23 37.36 Quite Low
metalloproteinase 6 32.08 Quite Low
fibrosis 7 9.12 Low Low
Inflammatory response 23 5.00 Very Low Very Low Very Low
cytokine 17 5.00 Very Low Very Low Very Low
Thoracotomy 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 2 98.60 Very High Very High Very High
Esophageal Cancer 78 92.56 High High
Cancer 181 90.16 High High
Disease 69 86.56 High High
Pressure Volume 2 Under Development 12 86.36 High High
Adult Respiratory Distress Syndrome 61 84.40 Quite High
Systemic Inflammatory Response Syndrome 66 81.28 Quite High
Lung Injury 6 76.92 Quite High
Colon Cancer 47 76.88 Quite High
Postoperative Complications 6 74.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After both laparoscopic and open colorectal surgery, we observed a significant increase of circulating CRP levels and this increase was similar between the two groups on POD 1 and POD 4.
Positive_regulation (increase) of POD
1) Confidence 0.39 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2988071 Disease Relevance 0.63 Pain Relevance 0
On POD 7, the count of CD4+T cells, CD8+T cells and CD45RO+T cells rose to the preoperative levels in LCR group.
Positive_regulation (rose) of POD in T cells
2) Confidence 0.34 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2988071 Disease Relevance 0.42 Pain Relevance 0.05
1 mRNA were upregulated at POD 5, then NAMPT, EGR1 and MMP9 mRNA.
Positive_regulation (upregulated) of POD
3) Confidence 0.07 Published 2010 Journal J Transl Med Section Body Doc Link PMC2984412 Disease Relevance 0.81 Pain Relevance 0.10
MUC1 and PDGFA were upregulated at POD 3 (p = 0.048 and 0.045), followed by recovery from POD 5 to POD 14.
Positive_regulation (upregulated) of POD
4) Confidence 0.05 Published 2010 Journal J Transl Med Section Body Doc Link PMC2984412 Disease Relevance 0.24 Pain Relevance 0.03
IL-6 was upregulated at POD 5 then decreased to the intraoperative baseline value.
Positive_regulation (upregulated) of POD
5) Confidence 0.05 Published 2010 Journal J Transl Med Section Body Doc Link PMC2984412 Disease Relevance 0.15 Pain Relevance 0.04
Also, no increase was noted on POD 1 in the closed group.
Neg (no) Positive_regulation (increase) of POD 1
6) Confidence 0.04 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2814196 Disease Relevance 0.89 Pain Relevance 0

General Comments

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