INT294087

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ERBB2, ERBB3) plasma membrane (ERBB2, ERBB3) nucleus (ERBB2, ERBB3)
cell proliferation (ERBB2) extracellular space (ERBB3) extracellular region (ERBB3)
ERBB2 (Homo sapiens)
ERBB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 40 89.76 High High
Toxicity 10 86.84 High High
Ovarian Cancer 50 80.24 Quite High
Carcinoma 3 80.00 Quite High
Fallopian Tube Neoplasms 3 59.48 Quite High
Cancer 28 41.52 Quite Low
Diarrhoea 5 31.28 Quite Low
Exanthema 3 30.52 Quite Low
Disease Progression 3 22.44 Low Low
Hypertension 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pertuzumab is a monoclonal antibody that inhibits dimerization of ERBB2 with EGFR, ERBB3, and ERBB4.
Negative_regulation (inhibits) of ERBB2 Binding (dimerization) of ERBB3
1) Confidence 0.08 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2814233 Disease Relevance 0.60 Pain Relevance 0

General Comments

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