INT294094

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.56 Pain Relevance 0

plasma membrane (TXK, Eltd1) signal transduction (Eltd1) nucleus (TXK) DNA binding (TXK) signal transducer activity (Eltd1) cytoplasm (TXK)

TXK (Homo sapiens) Eltd1 (Mus musculus)

Pain Link Frequency Relevance Heat Pain 2 5.00 nud 1 5.00

Disease Link Frequency Relevance Heat Carcinoma 3 88.64 Disease 40 71.96 Cancer 28 68.88 Ovarian Cancer 50 62.60 Appetite Loss 1 55.72 Fatigue 3 55.16 Hypertension 4 54.80 Diarrhoea 5 54.24 Toxicity 10 46.36 Fallopian Tube Neoplasms 3 41.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Gefitinib is a small molecule tyrosine kinase inhibitor that binds to the ATP-binding site of the EGF receptor and thereby prevents its activation.

tyrosine kinase Binding (binds) of EGF receptor

1) Confidence 0.00 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2814233 Disease Relevance 0.56 Pain Relevance 0

General Comments

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