INT294131

Context Info Confidence 0.30 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.09

cytosol (IDO1) small molecule metabolic process (IDO1) oxidoreductase activity (IDO1) cellular nitrogen compound metabolic process (IDO1)

Anatomy Link Frequency HGF 2 IDO1 (Homo sapiens)

Pain Link Frequency Relevance Heat COX2 4 99.72 Inflammation 46 50.00 cytokine 42 50.00 Inflammatory stimuli 10 5.00 dexamethasone 2 5.00 Spinal cord 1 5.00 tolerance 1 5.00 Arthritis 1 5.00 Pain 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 1 76.24 INFLAMMATION 56 50.00 Graft Vs Host Disease 5 5.00 Obesity 3 5.00 Injury 3 5.00 Arthritis 1 5.00 Frailty 1 5.00 Necrosis 1 5.00 Chromosome Aberrations 1 5.00 Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Differences in mRNA expression of IDO, HGF, COX2 and CIITA was consistently observed (Figure 5A).

Negative_regulation (Differences) of Transcription (expression) of IDO in HGF associated with cox2

1) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2814860 Disease Relevance 0.08 Pain Relevance 0.09

General Comments

This test has worked.