INT294204

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpine1, Plat) extracellular region (Serpine1, Plat) peptidase activity (Plat)
cytoplasm (Plat)
Serpine1 (Mus musculus)
Plat (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 20 40.92 Quite Low
Central nervous system 36 5.00 Very Low Very Low Very Low
isoflurane 16 5.00 Very Low Very Low Very Low
imagery 8 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Middle Cerebral Artery Infarction 68 50.44 Quite High
Stroke 108 50.00 Quite Low
Cv Unclassified Under Development 16 40.92 Quite Low
Cicatrix 16 26.00 Quite Low
Targeted Disruption 24 19.00 Low Low
Apoptosis 20 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
Injury 8 5.00 Very Low Very Low Very Low
Sprains And Strains 8 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When tPA is bound with PAI-1 or its other inhibitors, tPA is inactive [25]; conversely, tPA is active when unbound.
PAI Binding (bound) of tPA
1) Confidence 0.46 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2815778 Disease Relevance 0.10 Pain Relevance 0
Active mouse tPA binds to the biotinylated human PAI-1 coated on a microtiter, and an ELISA kit can be used to measure the active tPA in conditioned media.
PAI Binding (binds) of tPA
2) Confidence 0.46 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2815778 Disease Relevance 0 Pain Relevance 0
When tPA is bound with PAI-1 or its other inhibitors, tPA is inactive [25]; conversely, tPA is active when unbound.
PAI Binding (bound) of tPA
3) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2815778 Disease Relevance 0.05 Pain Relevance 0
When tPA is bound with PAI-1 or its other inhibitors, tPA is inactive [25]; conversely, tPA is active when unbound.
PAI Binding (bound) of tPA
4) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2815778 Disease Relevance 0.05 Pain Relevance 0

General Comments

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