INT294316

Context Info Confidence 0.22 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

extracellular space (IL6ST, IL11) extracellular region (IL6ST, IL11) plasma membrane (IL6ST) cell-cell signaling (IL11) cytoplasm (IL11)

Anatomy Link Frequency decidua 2 IL6ST (Homo sapiens) IL11 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 5 5.00 metalloproteinase 2 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Infection 3 15.52 Adhesions 2 5.00 Pain 1 5.00 Hyperplasia 1 5.00 Female Infertility 1 5.00 Hematological Disease 1 5.00 Spontaneous Abortion 1 5.00 Down Syndrome 1 5.00 Reprotox - General 3 1 5.00 Neurodegenerative Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

PROK1 induces the expression and secretion of IL-11 but not PROKR1 or GP130 in first trimester decidua via a Gq–Ca2+–ERK dependent pathway

GP130 Neg (not) Positive_regulation (induces) of Gene_expression (expression) of IL-11 in decidua

1) Confidence 0.22 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0

General Comments

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