INT294376

Context Info Confidence 0.34 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.10

plasma membrane (Psd) intracellular (Psd) cytoplasm (Psd)

Anatomy Link Frequency synapses 1 Psd (Mus musculus)

Pain Link Frequency Relevance Heat amygdala 2 75.08 Hippocampus 2 74.16 Central nervous system 11 58.88 gABA 9 50.00 GABAergic 17 26.16 GABA receptor 9 5.00 potassium channel 2 5.00 sodium channel 1 5.00 Neurotransmitter 1 5.00 Nav1.2 1 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 4 22.80 Targeted Disruption 8 5.00 Diabetes Mellitus 1 5.00 Tinnitus 1 5.00 Dislocations 1 5.00 Auditory Disease 1 5.00 Hypertrophy 1 5.00 Adhesions 1 5.00 Aging 1 5.00 Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Specifically, PSD93 is known to play a role in stabilization of receptor clusters at neuronal cholinergic synapses, and PSD scaffolding molecules are linked to cytoskeletal processes, transcriptional regulation and protein phosphorylation, and can relay the intracellular effects of synaptic activation [83].

Phosphorylation (phosphorylation) of PSD in synapses

1) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2816210 Disease Relevance 0 Pain Relevance 0.10

General Comments

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