INT294403

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Context Info
Confidence 0.80
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.96
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Vav3) intracellular (Vav3) cytoplasm (Vav3)
Anatomy Link Frequency
eye 1
Vav3 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 6 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 3 93.04 High High
Glaucoma 162 79.32 Quite High
Targeted Disruption 9 78.08 Quite High
Ocular Hypertension 171 75.48 Quite High
Optic Disorders 6 66.72 Quite High
Disease 6 50.00 Quite Low
Hydrophthalmos 15 8.24 Low Low
Ganglion Cysts 12 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Hyperplasia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Next, the Vav2 and Vav3 mRNA localization in mouse eye was examined by in situ hybridization (ISH) analysis (Figure 5B).
Localization (localization) of Vav3 mRNA in eye
1) Confidence 0.80 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2816215 Disease Relevance 0.19 Pain Relevance 0
The three mammalian Vav proteins, Vav1, Vav2, and Vav3, share a Dbl homology domain for their enzymatic activity as GEFs and contain a common structural array characteristic of proteins involved in signal transduction.
Localization (share) of Vav3
2) Confidence 0.75 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2816215 Disease Relevance 0.72 Pain Relevance 0
The co- localization of Vav2 and Vav3 mRNA expression in iridocorneal angle, such as TM, was confirmed by ISH.
Localization (localization) of Vav3 mRNA
3) Confidence 0.71 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2816215 Disease Relevance 0.05 Pain Relevance 0

General Comments

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