INT294407

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Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Vav3) intracellular (Vav3) cytoplasm (Vav3)
Vav3 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glaucoma 54 98.36 Very High Very High Very High
Blindness 1 89.64 High High
Ocular Hypertension 57 85.52 High High
Ganglion Cysts 4 80.40 Quite High
Disease 2 75.00 Quite High
Hydrophthalmos 5 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Optic Disorders 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we demonstrate that deficiency of Vav2 and Vav3, guanine nucleotides exchange factors for Rho guanosine triphosphatases, leads to an ocular phenotype similar to human glaucoma.
Positive_regulation (leads) of Negative_regulation (deficiency) of Vav3 associated with glaucoma
1) Confidence 0.50 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2816215 Disease Relevance 0.73 Pain Relevance 0

General Comments

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