INT29441

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Context Info
Confidence 0.20
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 5.97
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 2
Cea (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 6 94.20 High High
abdominal pain 2 88.48 High High
Chronic pancreatitis 4 88.04 High High
cryotherapy 4 80.12 Quite High
palliative 5 70.00 Quite High
Pain 5 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 144 99.24 Very High Very High Very High
Adenocarcinoma 1 98.56 Very High Very High Very High
Malignant Neoplastic Disease 8 97.28 Very High Very High Very High
Hepatotoxicity 15 95.96 Very High Very High Very High
Metastasis 74 94.60 High High
Disease 44 92.88 High High
Vomiting 6 90.96 High High
Lung Cancer 2 89.28 High High
Sarcoma 29 88.64 High High
Rhabdoid Tumor 4 88.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The only occasion in which CEA appeared to have a higher predictive value than CA 15-3 was in the subgroup of patients experiencing a PR, where the observed decrease in CEA levels attained statistical significance after 6 months.
Negative_regulation (decrease) of Gene_expression (levels) of CEA
1) Confidence 0.20 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1435763 Disease Relevance 0.53 Pain Relevance 0.07
Elevated serum CEA levels of more than 3.0ng/ml were decreased in 7/8 patients (87.5%).
Negative_regulation (decreased) of Gene_expression (levels) of CEA
2) Confidence 0.14 Published 1988 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 2831818 Disease Relevance 0.92 Pain Relevance 0.09
Some of our suggestions for the treatment of such malignancies as revealed herein include, total pancreatomy for univocal mass lesion, and needle aspiration of lesion-contained tissue for amylase, CA199 and CEA levels for a suspicious cystic pancreatic mass.
Negative_regulation (revealed) of Gene_expression (levels) of CEA
3) Confidence 0.11 Published 2005 Journal World J. Gastroenterol. Section Abstract Doc Link 16124071 Disease Relevance 1.16 Pain Relevance 0.35
Four patients did not have CEA levels measured after SIRT because of their deteriorating condition.
Negative_regulation (measured) of Gene_expression (levels) of CEA
4) Confidence 0.09 Published 2005 Journal BMC Nucl Med Section Body Doc Link PMC1360059 Disease Relevance 0.36 Pain Relevance 0
Its efficacy was shown by an improvement in most of the liver function tests in all patients and a decrease in serum CEA levels for three of four assessable patients with acceptable morbidity.
Negative_regulation (decrease) of Gene_expression (levels) of CEA in liver
5) Confidence 0.07 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2987942 Disease Relevance 0.72 Pain Relevance 0.04
Further, on IHC, lack of CK20 and CEA expression made a possibility of a metastatic adenocarcinoma from the GI tract as less likely.
Negative_regulation (lack) of Gene_expression (expression) of CEA associated with adenocarcinoma
6) Confidence 0.05 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1820783 Disease Relevance 2.28 Pain Relevance 0

General Comments

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