INT294679

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GPI, Il12a) extracellular space (GPI, Il12a) extracellular region (GPI, Il12a)
isomerase activity (GPI) small molecule metabolic process (GPI) carbohydrate metabolic process (GPI)
Anatomy Link Frequency
macrophages 2
GPI (Homo sapiens)
Il12a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 3 88.52 High High
cytokine 5 65.92 Quite High
Inflammation 9 39.28 Quite Low
chemokine 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 1 99.92 Very High Very High Very High
Necrosis 1 99.68 Very High Very High Very High
American Trypanosomiasis 1 94.32 High High
Infection 9 93.80 High High
INFLAMMATION 12 88.16 High High
Malaria 1 84.64 Quite High
Parasitemia 1 81.28 Quite High
Sprains And Strains 4 50.60 Quite High
Adhesions 6 48.24 Quite Low
Amebiasis 22 36.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GPI-anchored molecules purified from T. cruzi trypomastigotes signal through TLR2 and induce the production of IL-12, tumor necrosis factor (TNF)-alpha and nitric oxide by murine macrophages [81]; signaling through TLR2 synergizes with TLR9 and is crucial to control the infection [82].
GPI Positive_regulation (induce) of Gene_expression (production) of IL-12 in macrophages associated with necrosis, cancer and infection
1) Confidence 0.00 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2817369 Disease Relevance 0.69 Pain Relevance 0.08

General Comments

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