INT294725

Context Info Confidence 0.00 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.10

plasma membrane (LTB4R, LTB4R2) signal transducer activity (LTB4R, LTB4R2) signal transduction (LTB4R2)

Anatomy Link Frequency leukocytes 1 LTB4R (Homo sapiens) LTB4R2 (Homo sapiens)

Pain Link Frequency Relevance Heat Potency 2 69.60 agonist 1 63.84 cytokine 1 44.16 Inflammation 6 5.00 Angina 2 5.00 antagonist 2 5.00 ischemia 1 5.00 Pain 1 5.00 Inflammatory mediators 1 5.00 headache 1 5.00

Disease Link Frequency Relevance Heat Atherosclerosis 23 50.00 Adhesions 1 42.64 Disease 4 26.92 Hyperplasia 2 18.84 Aneurism 2 17.72 INFLAMMATION 8 13.20 Asthma 5 10.44 Rhinitis 3 7.88 Acute Coronary Syndrome 9 5.00 Cardiovascular Disease 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

BLT1 is a high-affinity receptor specific for LTB4, which is expressed primarily in leukocytes and mediates chemotaxis [25]; BLT2 is a pharmacologically distinct receptor, which is ubiquitously expressed and displays low affinity for LTB4 and also binds other eicosanoids [26, 27].

LTB4 Binding (affinity) of BLT2 in leukocytes

1) Confidence 0.00 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2817543 Disease Relevance 0 Pain Relevance 0.10

General Comments

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