INT294780

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, IL10) extracellular region (IL6, IL10) aging (IL6)
intracellular (IL10) cell-cell signaling (IL10) response to stress (IL10)
Anatomy Link Frequency
plasma 1
monocytes 1
IL6 (Homo sapiens)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 2 99.72 Very High Very High Very High
cytokine 43 96.48 Very High Very High Very High
Inflammation 12 96.08 Very High Very High Very High
chemokine 12 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 99.32 Very High Very High Very High
Mycobacterial Infection 27 97.96 Very High Very High Very High
Disease 16 88.60 High High
Influenza Virus Infection 15 88.28 High High
Critical Illness 37 82.32 Quite High
Infection 15 69.64 Quite High
Severe Acute Respiratory Syndrome 2 62.64 Quite High
Viremia 3 37.08 Quite Low
Respiratory Disease 3 5.00 Very Low Very Low Very Low
Weight Loss 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL6 is known to be responsible for regulating plasma levels of IL1RA and IL10 [16].
IL6 Positive_regulation (responsible) of IL10 in plasma
1) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2948498 Disease Relevance 1.11 Pain Relevance 0.35
and IL-6 but did not induce IL-10 or IL-12 in bronchoalveolar cells and monocytes (mean ± SD [pg/mL], TNF-?
IL-6 Neg (not) Positive_regulation (induce) of IL-10 in monocytes
2) Confidence 0.07 Published 2010 Journal Respir Res Section Body Doc Link PMC2817655 Disease Relevance 0.15 Pain Relevance 0.04

General Comments

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