INT294809

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.21
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Dlx1) nucleus (Dlx1) DNA binding (Dlx1)
Anatomy Link Frequency
neocortex 2
ventral 2
Dlx1 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 47 99.04 Very High Very High Very High
Spinal cord 1 71.12 Quite High
cerebral cortex 29 65.12 Quite High
Central nervous system 2 47.28 Quite Low
Hippocampus 14 5.00 Very Low Very Low Very Low
imagery 10 5.00 Very Low Very Low Very Low
interneuron 9 5.00 Very Low Very Low Very Low
Action potential 7 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
long-term potentiation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 45 74.80 Quite High
Epilepsy 8 69.12 Quite High
Convulsion 39 50.00 Quite Low
Apoptosis 9 45.76 Quite Low
Disease 3 21.80 Low Low
Stuttering 2 5.12 Low Low
Infection 37 5.00 Very Low Very Low Very Low
Injury 11 5.00 Very Low Very Low Very Low
Cognitive Disorder 7 5.00 Very Low Very Low Very Low
Anxiety Disorder 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At E12.5, expression of survivin overlapped with Dlx1, a marker for mitotic cells in the MGE and LGE [24] (Figure 1A, D) and neurogenin 2 (Ngn2) [25], a marker for dividing precursors in the neocortex (Figure 1A, C).
Positive_regulation (overlapped) of Gene_expression (expression) of Dlx1 in neocortex
1) Confidence 0.37 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2817683 Disease Relevance 0.21 Pain Relevance 0
Yet the fact that astroglial cells of dorsal telencephalic origin can be forced to adopt a “ventral” fate is consistent with previous findings that ventral transcription factors can instruct a GABAergic fate in dorsally derived progenitors including induction of endogenous Dlx gene expression [12],[58].
Positive_regulation (induction) of Gene_expression (expression) of Dlx gene in ventral associated with gabaergic
2) Confidence 0.06 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2872647 Disease Relevance 0 Pain Relevance 0.16

General Comments

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