INT294831

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.53 Pain Relevance 0

cytoplasm (DPYD, RASGRP1) cytosol (DPYD, RASGRP1) cell differentiation (RASGRP1) small molecule metabolic process (DPYD) Golgi apparatus (RASGRP1) endoplasmic reticulum (RASGRP1)

DPYD (Homo sapiens) RASGRP1 (Homo sapiens)

Pain Link Frequency Relevance Heat Spinal cord 12 5.00 Action potential 4 5.00 Sciatic nerve 3 5.00 Potency 3 5.00 anesthesia 1 5.00 withdrawal 1 5.00

Disease Link Frequency Relevance Heat Hypoxia 35 99.98 Stress 2 97.64 Chromosome Aberrations 1 76.48 Diabetes Mellitus 12 25.72 Spinal Cord Injury 15 5.00 Death 6 5.00 Obesity 6 5.00 Aging 6 5.00 Injury 4 5.00 Apoptosis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Hypoxia/DHP-d can activate ERK MAPKs via pathways independent or dependent [30] of Ras and Raf activation.

DHP-d Positive_regulation (activate) of Positive_regulation (activation) of Ras associated with hypoxia

1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2817727 Disease Relevance 0.53 Pain Relevance 0

General Comments

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