INT294861

Context Info Confidence 0.15 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.49 Pain Relevance 0

nucleolus (KLF4) nucleus (KLF4) intracellular (KLF4) DNA binding (KLF4)

KLF4 (Homo sapiens)

Pain Link Frequency Relevance Heat Spinal cord 12 5.00 Action potential 4 5.00 Sciatic nerve 3 5.00 Potency 3 5.00 anesthesia 1 5.00 withdrawal 1 5.00

Disease Link Frequency Relevance Heat Hypoxia 35 93.48 Injury 4 82.88 Wound Healing 2 72.64 Osteoporosis 1 26.80 Spinal Cord Injury 15 5.00 Diabetes Mellitus 12 5.00 Death 6 5.00 Obesity 6 5.00 Aging 6 5.00 Apoptosis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

siRNA transfection prominently induced downregulated stemness genes expression, such as Rex1, Sox2, Oct4, and Klf4 with prominent growth attenuation (Figure 3E, 3F).

Positive_regulation (induced) of Klf4

1) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2817727 Disease Relevance 0.49 Pain Relevance 0

General Comments

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