INT294907

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.45
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) extracellular region (Il6)
Anatomy Link Frequency
astrocytes 1
Il1 (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 57 100.00 Very High Very High Very High
chemokine 1 85.36 High High
Inflammation 11 80.56 Quite High
cytokine 20 75.68 Quite High
Neuropeptide 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Granuloma 92 95.24 Very High Very High Very High
Targeted Disruption 42 94.12 High High
INFLAMMATION 8 80.56 Quite High
Cyst 12 73.84 Quite High
Infection 12 50.00 Quite Low
Mycobacterial Infection 1 47.92 Quite Low
Cestode Infection 10 5.00 Very Low Very Low Very Low
Neurocysticercosis 8 5.00 Very Low Very Low Very Low
Convulsion 5 5.00 Very Low Very Low Very Low
Granulomatous Inflammation 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-6 production in human peripheral blood mononuclear cells, bronchial cells, and astrocytes is increased directly by SP through the action of nuclear factor IL-6 (NF-IL-6) and p38 MAPK, as well as indirectly in response to IL-1?
IL-1 Positive_regulation (increased) of IL-6 in astrocytes associated with substance p
1) Confidence 0.06 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2817809 Disease Relevance 1.45 Pain Relevance 0.29

General Comments

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