INT294911

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.78
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Pax3) extracellular space (Il6) extracellular region (Il6)
nucleus (Pax3) DNA binding (Pax3)
Anatomy Link Frequency
astrocytes 2
Pax3 (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 114 100.00 Very High Very High Very High
Neuropeptide 4 92.24 High High
chemokine 2 80.08 Quite High
cytokine 40 75.68 Quite High
Inflammation 22 75.28 Quite High
Inflammatory response 2 26.60 Quite Low
Central nervous system 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Granuloma 184 95.24 Very High Very High Very High
Targeted Disruption 84 94.12 High High
INFLAMMATION 16 75.28 Quite High
Cyst 24 73.84 Quite High
Infection 24 50.00 Quite Low
Mycobacterial Infection 2 47.92 Quite Low
Anaplastic Astrocytoma 2 39.76 Quite Low
Schistosomiasis 4 28.96 Quite Low
Cestode Infection 20 5.00 Very Low Very Low Very Low
Neurocysticercosis 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also IL-6 production in human peripheral blood mononuclear cells, bronchial cells, and astrocytes is increased directly by SP through the action of nuclear factor IL-6 (NF-IL-6) and p38 MAPK [26, 27, 34, 35].
SP Positive_regulation (increased) of IL-6 in astrocytes associated with substance p
1) Confidence 0.06 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2817809 Disease Relevance 0.41 Pain Relevance 0.86
IL-6 production in human peripheral blood mononuclear cells, bronchial cells, and astrocytes is increased directly by SP through the action of nuclear factor IL-6 (NF-IL-6) and p38 MAPK, as well as indirectly in response to IL-1?
SP Positive_regulation (increased) of IL-6 in astrocytes associated with substance p
2) Confidence 0.06 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2817809 Disease Relevance 1.37 Pain Relevance 0.29

General Comments

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