INT294984

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Context Info
Confidence 0.52
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (BDP1) nucleus (BDP1) DNA binding (BDP1)
Anatomy Link Frequency
plasma 1
BDP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 57.48 Quite High
Ziconotide 2 54.52 Quite High
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 20 93.48 High High
Malignant Neoplastic Disease 2 86.72 High High
Stress 20 82.72 Quite High
Apoptosis 44 81.84 Quite High
Death 6 67.56 Quite High
Ovarian Cancer 2 65.60 Quite High
Colon Cancer 12 61.84 Quite High
Pain 2 57.48 Quite High
Recurrence 2 24.88 Low Low
Lung Cancer 2 17.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Iron in the serum is coupled to Tfn before endocytosis into the cell via interaction with its ligand receptors on the plasma membrane, and iron is then released from the Tfn-TfnR complex in the endosomes before both Tfn and TfnR are returned to the plasma membrane through recycling endosomes [11].
Localization (released) of Tfn-TfnR in plasma
1) Confidence 0.52 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2817924 Disease Relevance 0.44 Pain Relevance 0
Once the iron is released from the Tfn, the Tfn-TfnR complex is recycled either directly or indirectly through the Golgi complex back to the cell surface [10].
Localization (released) of Tfn-TfnR
2) Confidence 0.52 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2817924 Disease Relevance 0.76 Pain Relevance 0.11

General Comments

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