INT294997

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.81
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Tnfsf11) extracellular space (Tnfsf11) extracellular region (Tnfsf11)
plasma membrane (Tnfsf11) intracellular (Tnfsf11) response to stress (Tnfsf11)
Tnfsf11 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 3 93.48 High High
Angina 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 6 97.68 Very High Very High Very High
Rheumatoid Arthritis 3 93.48 High High
Osteoporosis 9 92.52 High High
Overweight 6 50.00 Quite Low
Obesity 3 39.04 Quite Low
Hypercalcemia 15 5.00 Very Low Very Low Very Low
Nicotine Addiction 12 5.00 Very Low Very Low Very Low
Weight Loss 6 5.00 Very Low Very Low Very Low
Rickets 6 5.00 Very Low Very Low Very Low
Infarction 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, the lack of corresponding changes in serum levels indicate that the circulating levels of OPG and RANKL do not reflect the concentrations in the local tissues [27].
Regulation (circulating) of Gene_expression (levels) of RANKL
1) Confidence 0.35 Published 2010 Journal Nutr J Section Body Doc Link PMC2818614 Disease Relevance 0.26 Pain Relevance 0.04
Therefore, the lack of corresponding changes in serum levels indicate that the circulating levels of OPG and RANKL do not reflect the concentrations in the local tissues [27].
Neg (not) Regulation (reflect) of Gene_expression (levels) of RANKL
2) Confidence 0.35 Published 2010 Journal Nutr J Section Body Doc Link PMC2818614 Disease Relevance 0.26 Pain Relevance 0.04
Most likely oestrogen, as well as bisphosphonates, influence the production of OPG and RANKL as demonstrated in in-vitro studies [32,33].
Regulation (influence) of Gene_expression (production) of RANKL
3) Confidence 0.21 Published 2010 Journal Nutr J Section Body Doc Link PMC2818614 Disease Relevance 0.28 Pain Relevance 0.05

General Comments

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