INT295003

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.85
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tnfrsf11b, Tnfsf11) extracellular region (Tnfrsf11b, Tnfsf11) cell differentiation (Tnfsf11)
signal transduction (Tnfrsf11b) proteinaceous extracellular matrix (Tnfrsf11b) plasma membrane (Tnfsf11)
Anatomy Link Frequency
stromal cells 1
osteoblasts 1
Tnfrsf11b (Rattus norvegicus)
Tnfsf11 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 2 86.56 High High
cytokine 1 78.00 Quite High
corticosteroid 2 16.72 Low Low
cva 10 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
peripheral neuropathy 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
induced neuropathy 2 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 10 99.12 Very High Very High Very High
Bone Cancer 4 95.68 Very High Very High Very High
Hypercalcemia 12 87.80 High High
Rheumatoid Arthritis 2 86.56 High High
Multiple Myeloma 29 82.32 Quite High
Disease 26 77.12 Quite High
Herpes Zoster 2 75.00 Quite High
Rickets 4 73.24 Quite High
Hypocalcemia 2 72.12 Quite High
Sunburn 2 66.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, both serum OPG and RANKL have been found to decrease after treatment with oestrogen in postmenopausal women in one study [28], whereas serum OPG but not RANKL increased after oral contraceptives in another study [29].
serum OPG Binding (found) of RANKL
1) Confidence 0.22 Published 2010 Journal Nutr J Section Body Doc Link PMC2818614 Disease Relevance 0.25 Pain Relevance 0.04
The osteoblasts also produce OPG which functions as a decoy receptor and binds RANKL and thereby prevents it from binding to RANK [2,7].
OPG Binding (binds) of RANKL in osteoblasts
2) Confidence 0.19 Published 2010 Journal Nutr J Section Body Doc Link PMC2818614 Disease Relevance 0.51 Pain Relevance 0
The RANK ligand (RANKL) and a regulatory protein, osteoprotegerin, produced by stromal cells both bind RANK.
osteoprotegerin Binding (ligand) of RANKL in stromal cells
3) Confidence 0.13 Published 2010 Journal Advances in Hematology Section Body Doc Link PMC2905716 Disease Relevance 1.09 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox