INT295036

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.34
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cdk2) cytoplasm (Cdk2) cytosol (Cdk2)
mitosis (Cdk2) nucleus (Cdk2) cytoskeleton (Cdk2)
Cdk2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 7 99.62 Very High Very High Very High
Apoptosis 33 86.68 High High
Cancer 95 81.00 Quite High
Targeted Disruption 2 74.88 Quite High
Toxicity 3 63.60 Quite High
Syndrome 1 61.28 Quite High
Cytomegalovirus Infection 66 5.00 Very Low Very Low Very Low
Infection 27 5.00 Very Low Very Low Very Low
Melanoma 15 5.00 Very Low Very Low Very Low
Metastasis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
UTR (corresponding to nt 1180–2606 of the Entrez PubMed transcript BC095407) was PCR amplified from a pBluescriptR vector containing CREB1 full length cDNA (Open Biosystems); The PCR products were cloned into pGL3-control luciferase reporter vector (Promega) via an XbaI restriction site, immediately downstream of the luciferase gene; a 38 bp fragment of the human CDK2 mRNA 3?
Positive_regulation (cloned) of Positive_regulation (fragment) of CDK2
1) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944884 Disease Relevance 0 Pain Relevance 0
Maddika et al indicated that inhibitors of PI3-kinase or Akt not only inhibited CDK2 activation but also protected cells from Apoptin-induced cell death, and Akt-mediated activation of CDK2 was caused by direct phosphorylation as well as by the phosphorylation-induced degradation of its inhibitor p27 (Kip1) [32].
Positive_regulation (caused) of Positive_regulation (activation) of CDK2 associated with death
2) Confidence 0.26 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2818692 Disease Relevance 0.93 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox